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Cortactin promotes colorectal cancer cell proliferation by activating the EGFR-MAPK pathway

Cortactin (CTTN) is overexpressed in various tumors, including head and neck squamous cell carcinoma and colorectal cancer (CRC), and can serve as a biomarker of cancer metastasis. We observed that CTTN promotes cancer cell proliferation in vitro and increases CRC tumor xenograft growth in vivo. CTT...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Zhang, Xiaojian, Liu, Kun, Zhang, Tao, Wang, Zhenlei, Qin, Xuan, Jing, Xiaoqian, Wu, Haoxuan, Ji, Xiaopin, He, Yonggang, Zhao, Ren
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5352075/
https://ncbi.nlm.nih.gov/pubmed/27903975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13652
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