GDF15 contributes to radioresistance and cancer stemness of head and neck cancer by regulating cellular reactive oxygen species via a SMAD-associated signaling pathway

Radiotherapy is an integral part for the treatment of head and neck cancer (HNC), while radioresistance is a major cause leads to treatment failure. GDF15, a member of the TGF-β superfamily, is hypothesized to participate in various types of homeostasis. However, the potential role of this molecule...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Li, Yan-Liang, Chang, Joseph T., Lee, Li-Yu, Fan, Kang-Hsing, Lu, Ya-Ching, Li, Yi-Chen, Chiang, Chang-Hsu, You, Guo-Rung, Chen, Hsin-Ying, Cheng, Ann-Joy
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5352073/
https://ncbi.nlm.nih.gov/pubmed/27903972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13649
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