Germline compound heterozygous poly-glutamine deletion in USF3 may be involved in predisposition to heritable and sporadic epithelial thyroid carcinoma

Cowden syndrome (CS) is an autosomal dominant disorder that predisposes to breast, thyroid, and other epithelial cancers. Differentiated thyroid carcinoma (DTC), as one of the major component cancers of CS, is the fastest rising incident cancer in the USA, and the most familial of all solid tumours....

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Pubblicato in:Hum Mol Genet
Autori principali: Ni, Ying, Seballos, Spencer, Fletcher, Benjamin, Romigh, Todd, Yehia, Lamis, Mester, Jessica, Senter, Leigha, Niazi, Farshad, Saji, Motoyasu, Ringel, Matthew D., LaFramboise, Thomas, Eng, Charis
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2017
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5351935/
https://ncbi.nlm.nih.gov/pubmed/28011713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddw382
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