Germline compound heterozygous poly-glutamine deletion in USF3 may be involved in predisposition to heritable and sporadic epithelial thyroid carcinoma

Cowden syndrome (CS) is an autosomal dominant disorder that predisposes to breast, thyroid, and other epithelial cancers. Differentiated thyroid carcinoma (DTC), as one of the major component cancers of CS, is the fastest rising incident cancer in the USA, and the most familial of all solid tumours....

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Detalhes bibliográficos
Publicado no:Hum Mol Genet
Main Authors: Ni, Ying, Seballos, Spencer, Fletcher, Benjamin, Romigh, Todd, Yehia, Lamis, Mester, Jessica, Senter, Leigha, Niazi, Farshad, Saji, Motoyasu, Ringel, Matthew D., LaFramboise, Thomas, Eng, Charis
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5351935/
https://ncbi.nlm.nih.gov/pubmed/28011713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddw382
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