GAK is phosphorylated by c-Src and translocated from the centrosome to chromatin at the end of telophase

Cyclin G-associated kinase (GAK) harbors a consensus phosphorylation motif (Y412) for c-Src; however, its physiological significance remains elusive. Here, we show that GAK is phosphorylated by c-Src not only at Y412 but also at Y1149. An anti-GAK-pY412 antibody recognized the shifted band of GAK du...

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Publicat a:Cell Cycle
Autors principals: Fukushima, Kohshiro, Wang, Mian, Naito, Yoko, Uchihashi, Toshihiro, Kato, Yorika, Mukai, Satomi, Yabuta, Norikazu, Nojima, Hiroshi
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2017
Matèries:
Reports
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5351929/
https://ncbi.nlm.nih.gov/pubmed/28135906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2016.1241916
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