Mutations in TP53, PIK3CA, PTEN and other genes in EGFR mutated lung cancers: correlation with clinical outcomes

INTRODUCTION: The degree and duration of response to epidermal growth factor receptor (EGFR) inhibitors in EGFR mutated lung cancer are heterogeneous. We hypothesized that the concurrent genomic landscape of these tumors, which is currently unknown in view of the prevailing single gene assay diagnos...

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Publicado no:Lung Cancer
Main Authors: VanderLaan, Paul A., Rangachari, Deepa, Mockus, Susan M., Spotlow, Vanessa, Reddi, Honey V., Malcolm, Joan, Huberman, Mark S., Joseph, Loren J., Kobayashi, Susumu S., Costa, Daniel B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5351777/
https://ncbi.nlm.nih.gov/pubmed/28285689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.lungcan.2017.01.011
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