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HER3 and LINC00052 interplay promotes tumor growth in breast cancer

Here we report that the lncRNA LINC00052 expression correlates positively with HER3/ErbB3 levels in breast cancer cells. Gene silencing of LINC00052 diminished both LINC00052 and HER3 expression and reduced cancer cell growth in vitro and in vivo. LINC00052 overexpression promoted cancer cell growth...

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Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Salameh, Ahmad, Fan, Xuejun, Choi, Byung-Kwon, Zhang, Shu, Zhang, Ningyan, An, Zhiqiang
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5351650/
https://ncbi.nlm.nih.gov/pubmed/28036286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14313
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