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Novel association of DJ-1 with HER3 potentiates HER3 activation and signaling in cancer

HER3/ErbB3 has emerged as a new therapeutic target for cancer. Currently, more than a dozen anti-HER3 antibodies are in clinical trials for treatment of various cancers. However, limited understanding of the complex HER3 signaling in cancer and lack of established biomarkers have made it challenging...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Zhang, Shu, Mukherjee, Seema, Fan, Xuejun, Salameh, Ahmad, Mujoo, Kalpana, Huang, Zhao, Li, Leike, Salazar, Georgina To'a, Zhang, Ningyan, An, Zhiqiang
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5323190/
https://ncbi.nlm.nih.gov/pubmed/27582551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11613
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