Genome-wide methylation sequencing of paired primary and metastatic cell lines identifies common DNA methylation changes and a role for EBF3 as a candidate epigenetic driver of melanoma metastasis

Epigenetic alterations are increasingly implicated in metastasis, whereas very few genetic mutations have been identified as authentic drivers of cancer metastasis. Yet, to date, few studies have identified metastasis-related epigenetic drivers, in part because a framework for identifying driver epi...

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Detalles Bibliográficos
Publicado en:Oncotarget
Autores principales: Chatterjee, Aniruddha, Stockwell, Peter A, Ahn, Antonio, Rodger, Euan J, Leichter, Anna L, Eccles, Michael R
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5351615/
https://ncbi.nlm.nih.gov/pubmed/28030832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14042
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