Extensive Inter-Cyst DNA Methylation Variation in Autosomal Dominant Polycystic Kidney Disease Revealed by Genome Scale Sequencing

Autosomal dominant polycystic kidney disease (ADPKD) is a heritable disease characterized by bilateral renal enlargement due to the growth of cysts throughout the kidneys. Inheritance of a disease-causing mutation is required to develop ADPKD, which results in end-stage kidney disease and is associa...

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Detalhes bibliográficos
Publicado no:Front Genet
Main Authors: Bowden, Sarah A., Stockwell, Peter A., Rodger, Euan J., Parry, Matthew F., Eccles, Michael R., Stayner, Cherie, Chatterjee, Aniruddha
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Genetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7174623/
https://ncbi.nlm.nih.gov/pubmed/32351541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2020.00348
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