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Fenofibrate Attenuates Neutrophilic Inflammation in Airway Epithelia: Potential Drug Repurposing for Cystic Fibrosis

A hallmark of cystic fibrosis (CF) lung disease is neutrophilic airway inflammation. Elevated neutrophil counts have been associated with decreased forced expiratory volume in 1 second and poor clinical measures in patients with CF. Interleukin 8 (IL‐8), epithelial neutrophil activating protein 78 (...

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Bibliografiske detaljer
Udgivet i:Clin Transl Sci
Main Authors: Stolarz, Amanda J., Farris, Ryan A., Wiley, Charla A., O'Brien, Catherine E., Price, Elvin T.
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5351137/
https://ncbi.nlm.nih.gov/pubmed/26258991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cts.12310
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