Enhanced GRK2 Expression and Desensitization of βAR Vasodilatation in Hypertensive Patients

Increased levels of G protein coupled receptor kinase GRK2 appear to participate in hypertension presumably through the desensitization of β adrenergic receptors (βARs) that mediate vasodilatation. There are contrasting data on the occurrence of βAR desensitization in the vasculature, we therefore i...

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Vydáno v:Clin Transl Sci
Hlavní autoři: Izzo, Raffaele, Cipolletta, Ersilia, Ciccarelli, Michele, Campanile, Alfonso, Santulli, Gaetano, Palumbo, Gianluigi, Vasta, Antonio, Formisano, Salvatore, Trimarco, Bruno, Iaccarino, Guido
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Publishing Inc 2008
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5350663/
https://ncbi.nlm.nih.gov/pubmed/20443852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1752-8062.2008.00050.x
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