Loss of protohaem IX farnesyltransferase in mature dentate granule cells impairs short‐term facilitation at mossy fibre to CA3 pyramidal cell synapses

KEY POINTS: Neurodegenerative disorders can exhibit dysfunctional mitochondrial respiratory chain complex IV activity. Conditional deletion of cytochrome c oxidase, the terminal enzyme in the respiratory electron transport chain of mitochondria, from hippocampal dentate granule cells in mice does no...

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Bibliografske podrobnosti
izdano v:J Physiol
Main Authors: Booker, Sam A., Campbell, Graham R., Mysiak, Karolina S., Brophy, Peter J., Kind, Peter C., Mahad, Don J., Wyllie, David J. A.
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2017
Teme:
Neuroscience ‐ cellular/molecular
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5350446/
https://ncbi.nlm.nih.gov/pubmed/28083896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP273581
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