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Burst firing induces postsynaptic LTD at developing mossy fibre–CA3 pyramid synapses

Synaptic development is an activity-dependent process utilizing coordinated network activity to drive synaptogenesis and subsequent refinement of immature connections. Hippocampal CA3 pyramidal neurons (PYRs) exhibit intense burst firing (BF) early in development, concomitant with the period of moss...

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Autores principales: Ho, T M, Pelkey, K A, Pelletier, J G, Huganir, R L, Lacaille, J-C, McBain, C J
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Science Inc 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2766649/
https://ncbi.nlm.nih.gov/pubmed/19635819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2009.173880
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