Up-regulation of GLT-1 severely impairs LTD at mossy fibre–CA3 synapses

Glutamate transporters are responsible for clearing synaptically released glutamate from the extracellular space. By this action, they maintain low levels of ambient glutamate, thus preventing excitotoxic damage, and contribute to shaping synaptic currents. We show that up-regulation of the glutamat...

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Autors principals: Omrani, Azar, Melone, Marcello, Bellesi, Michele, Safiulina, Victoria, Aida, Tomomi, Tanaka, Kohishi, Cherubini, Enrico, Conti, Fiorenzo
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2009
Matèries:
Neuroscience
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2768014/
https://ncbi.nlm.nih.gov/pubmed/19651762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2009.177881
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