Up-regulation of GLT-1 severely impairs LTD at mossy fibre–CA3 synapses

Glutamate transporters are responsible for clearing synaptically released glutamate from the extracellular space. By this action, they maintain low levels of ambient glutamate, thus preventing excitotoxic damage, and contribute to shaping synaptic currents. We show that up-regulation of the glutamat...

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Detalhes bibliográficos
Main Authors: Omrani, Azar, Melone, Marcello, Bellesi, Michele, Safiulina, Victoria, Aida, Tomomi, Tanaka, Kohishi, Cherubini, Enrico, Conti, Fiorenzo
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2009
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2768014/
https://ncbi.nlm.nih.gov/pubmed/19651762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2009.177881
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