Up-regulation of GLT-1 severely impairs LTD at mossy fibre–CA3 synapses

Glutamate transporters are responsible for clearing synaptically released glutamate from the extracellular space. By this action, they maintain low levels of ambient glutamate, thus preventing excitotoxic damage, and contribute to shaping synaptic currents. We show that up-regulation of the glutamat...

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Main Authors: Omrani, Azar, Melone, Marcello, Bellesi, Michele, Safiulina, Victoria, Aida, Tomomi, Tanaka, Kohishi, Cherubini, Enrico, Conti, Fiorenzo
格式: Artigo
語言:Inglês
出版: Blackwell Science Inc 2009
主題:
Neuroscience
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2768014/
https://ncbi.nlm.nih.gov/pubmed/19651762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2009.177881
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