Up-regulation of GLT-1 severely impairs LTD at mossy fibre–CA3 synapses

Glutamate transporters are responsible for clearing synaptically released glutamate from the extracellular space. By this action, they maintain low levels of ambient glutamate, thus preventing excitotoxic damage, and contribute to shaping synaptic currents. We show that up-regulation of the glutamat...

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Dettagli Bibliografici
Autori principali: Omrani, Azar, Melone, Marcello, Bellesi, Michele, Safiulina, Victoria, Aida, Tomomi, Tanaka, Kohishi, Cherubini, Enrico, Conti, Fiorenzo
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 2009
Soggetti:
Neuroscience
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2768014/
https://ncbi.nlm.nih.gov/pubmed/19651762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2009.177881
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