Загрузка...
High‐fat diet induces protein kinase A and G‐protein receptor kinase phosphorylation of β(2)‐adrenergic receptor and impairs cardiac adrenergic reserve in animal hearts
KEY POINTS: Patients with diabetes show a blunted cardiac inotropic response to β‐adrenergic stimulation despite normal cardiac contractile reserve. Acute insulin stimulation impairs β‐adrenergically induced contractile function in isolated cardiomyocytes and Langendorff‐perfused hearts. In this stu...
Сохранить в:
| Опубликовано в: : | J Physiol |
|---|---|
| Главные авторы: | , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
John Wiley and Sons Inc.
2017
|
| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5350441/ https://ncbi.nlm.nih.gov/pubmed/27983752 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP273314 |
| Метки: |
Добавить метку
Нет меток, Требуется 1-ая метка записи!
|