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Transthyretin and BRICHOS: The Paradox of Amyloidogenic Proteins with Anti-Amyloidogenic Activity for Aβ in the Central Nervous System

Amyloid fibrils are physiologically insoluble biophysically specific β-sheet rich structures formed by the aggregation of misfolded proteins. In vivo tissue amyloid formation is responsible for more than 30 different disease states in humans and other mammals. One of these, Alzheimer's disease...

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Bibliografische gegevens
Gepubliceerd in:Front Neurosci
Hoofdauteurs: Buxbaum, Joel N., Johansson, Jan
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2017
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5350149/
https://ncbi.nlm.nih.gov/pubmed/28360830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2017.00119
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