VENTX induces expansion of primitive erythroid cells and contributes to the development of acute myeloid leukemia in mice

Homeobox genes are key regulators in normal and malignant hematopoiesis. The human Vent-like homeobox gene VENTX, a putative homolog of the Xenopus laevis Xvent-2 gene, was shown to be highly expressed in normal myeloid cells and in patients with acute myeloid leukemia. We now demonstrate that const...

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Udgivet i:Oncotarget
Main Authors: Gentner, Eva, Vegi, Naidu M., Mulaw, Medhanie A., Mandal, Tamoghna, Bamezai, Shiva, Claus, Rainer, Tasdogan, Alpaslan, Quintanilla-Martinez, Leticia, Grunenberg, Alexander, Döhner, Konstanze, Döhner, Hartmut, Bullinger, Lars, Haferlach, Torsten, Buske, Christian, Rawat, Vijay P.S., Feuring-Buske, Michaela
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2016
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5349961/
https://ncbi.nlm.nih.gov/pubmed/27888632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13563
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