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Epigenetic inhibition of miR-663b by long non-coding RNA HOTAIR promotes pancreatic cancer cell proliferation via up-regulation of insulin-like growth factor 2

Pancreatic cancer is one of the most deadly cancers with a poor prognosis. Although microRNAs are involving in the carcinogenesis and development of pancreatic cancer, little information is known regarding the role of miR-663b in pancreatic cancer. In this study, the expression of miR-663b in pancre...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Oncotarget
Hauptverfasser: Cai, Huihua, An, Yong, Chen, Xuemin, Sun, Donglin, Chen, Tongbing, Peng, Yan, Zhu, Feng, Jiang, Yong, He, Xiaozhou
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5349959/
https://ncbi.nlm.nih.gov/pubmed/27895308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13490
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