Niclosamide and its analogs are potent inhibitors of Wnt/β-catenin, mTOR and STAT3 signaling in ovarian cancer

Epithelial ovarian cancer (EOC) is the leading cause of gynecologic cancer mortality worldwide. Platinum-based therapy is the standard first line treatment and while most patients initially respond, resistance to chemotherapy usually arises. Major signaling pathways frequently upregulated in chemore...

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Enregistré dans:
Détails bibliographiques
Publié dans:Oncotarget
Auteurs principaux: Arend, Rebecca C., Londoño-Joshi, Angelina I., Gangrade, Abhishek, Katre, Ashwini A., Kurpad, Chandrika, Li, Yonghe, Samant, Rajeev S., Li, Pui-Kai, Landen, Charles N., Yang, Eddy S., Hidalgo, Bertha, Alvarez, Ronald D., Michael Straughn, John, Forero, Andres, Buchsbaum, Donald J.
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2016
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5349955/
https://ncbi.nlm.nih.gov/pubmed/27888804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13466
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