Gene and microRNA modulation upon trabectedin treatment in a human intrahepatic cholangiocarcinoma paired patient derived xenograft and cell line

Intrahepatic cholangiocarcinoma (ICC) is an aggressive and lethal malignancy with limited therapeutic options. Trabectedin has a high antitumor activity in preclinical models of biliary tract carcinoma (BTC), being a promising alternative treatment. Here, we studied the effect of trabectedin at tran...

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Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Peraldo Neia, Caterina, Cavalloni, Giuliana, Chiorino, Giovanna, Ostano, Paola, Aglietta, Massimo, Leone, Francesco
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2016
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5349952/
https://ncbi.nlm.nih.gov/pubmed/27902465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13575
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