Suppression of hepatic stellate cell activation through downregulation of gremlin1 expression by the miR-23b/27b cluster

The imbalance between transforming growth factor β and bone morphogenetic protein 7 signaling pathways is a critical step in promoting hepatic stellate cell activation during hepatic fibrogenesis. Gremlin1 may impair the balance. Something remains unclear about the regulatory mechanisms of gremlin1...

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Udgivet i:Oncotarget
Main Authors: Zeng, Xian-Yi, Zhang, Yan-Qiong, He, Xiao-Min, Wan, Lin-Yan, Wang, Hu, Ni, Yi-Ran, Wang, Jie, Wu, Jiang-Feng, Liu, Chang-Bai
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2016
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5349907/
https://ncbi.nlm.nih.gov/pubmed/27863390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13365
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