miR-23∼27∼24 clusters control effector T cell differentiation and function

Coordinated repression of gene expression by evolutionarily conserved microRNA (miRNA) clusters and paralogs ensures that miRNAs efficiently exert their biological impact. Combining both loss- and gain-of-function genetic approaches, we show that the miR-23∼27∼24 clusters regulate multiple aspects o...

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Detalhes bibliográficos
Publicado no:J Exp Med
Main Authors: Cho, Sunglim, Wu, Cheng-Jang, Yasuda, Tomoharu, Cruz, Leilani O., Khan, Aly Azeem, Lin, Ling-Li, Nguyen, Duc T., Miller, Marina, Lee, Hyang-Mi, Kuo, Ming-Ling, Broide, David H., Rajewsky, Klaus, Rudensky, Alexander Y., Lu, Li-Fan
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2016
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4749926/
https://ncbi.nlm.nih.gov/pubmed/26834155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20150990
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