Gli1 promotes colorectal cancer metastasis in a Foxm1-dependent manner by activating EMT and PI3K-AKT signaling

Colorectal cancer(CRC) is one of the most commonly diagnosed cancers in human beings and metastasis is the main death reason. Recently, Gli1 has been reported to be a key regulator of various cancer biologies and genes expressions. However, the detailed molecular mechanism of Gli1 in CRC metastasis...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Oncotarget
Main Authors: Zhang, Chuan, Wang, Yong, Feng, YiFei, Zhang, Yue, Ji, Bing, Wang, Sen, Sun, Ye, Zhu, Chunyan, Zhang, Dongsheng, Sun, Yueming
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2016
Teme:
Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5349902/
https://ncbi.nlm.nih.gov/pubmed/27863385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13348
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