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Decreased Gaq expression in T cells correlates with enhanced cytokine production and disease activity in systemic lupus erythematosus
Aberrant T cell immune responses appear central to the development of systemic lupus erythematosus (SLE). We previously reported that Gαq, the alpha subunit of Gq, regulates T and B cell immune responses, promoting autoimmunity. To address whether Gαq contributes to the pathogenesis of SLE, Gαq mRNA...
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| Publicado no: | Oncotarget |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Impact Journals LLC
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5349870/ https://ncbi.nlm.nih.gov/pubmed/27965465 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13903 |
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