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An essential dual-function complex mediates erythrocyte invasion and channel-mediated nutrient uptake in malaria parasites

Malaria parasites evade immune detection by growth and replication within erythrocytes. After erythrocyte invasion, the intracellular pathogen must increase host cell uptake of nutrients from plasma. Here, we report that the parasite-encoded RhopH complex contributes to both invasion and channel-med...

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Библиографические подробности
Опубликовано в: :eLife
Главные авторы: Ito, Daisuke, Schureck, Marc A, Desai, Sanjay A
Формат: Artigo
Язык:Inglês
Опубликовано: eLife Sciences Publications, Ltd 2017
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5349850/
https://ncbi.nlm.nih.gov/pubmed/28221136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.23485
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