Malaria parasites use a soluble RhopH complex for erythrocyte invasion and an integral form for nutrient uptake

Malaria parasites use the RhopH complex for erythrocyte invasion and channel-mediated nutrient uptake. As the member proteins are unique to Plasmodium spp., how they interact and traffic through subcellular sites to serve these essential functions is unknown. We show that RhopH is synthesized as a s...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Schureck, Marc A, Darling, Joseph E, Merk, Alan, Shao, Jinfeng, Daggupati, Geervani, Srinivasan, Prakash, Olinares, Paul Dominic B, Rout, Michael P, Chait, Brian T, Wollenberg, Kurt, Subramaniam, Sriram, Desai, Sanjay A
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2021
Assuntos:
Microbiology and Infectious Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7840181/
https://ncbi.nlm.nih.gov/pubmed/33393463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.65282
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