Structural basis for inhibition of erythrocyte invasion by antibodies to Plasmodium falciparum protein CyRPA

Plasmodium falciparum causes malaria in humans with over 450,000 deaths annually. The asexual blood stage involves invasion of erythrocytes by merozoites, in which they grow and divide to release daughter merozoites, which in turn invade new erythrocytes perpetuating the cycle responsible for malari...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Chen, Lin, Xu, Yibin, Wong, Wilson, Thompson, Jennifer K, Healer, Julie, Goddard-Borger, Ethan D, Lawrence, Michael C, Cowman, Alan F
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2017
Assuntos:
Biochemistry
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5349848/
https://ncbi.nlm.nih.gov/pubmed/28195530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.21347
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