Endostatin inhibits androgen-independent prostate cancer growth by suppressing nuclear receptor-mediated oxidative stress

Androgen-deprivation therapy has been identified to induce oxidative stress in prostate cancer (PCa), leading to reactivation of androgen receptor (AR) signaling in a hormone-refractory manner. Thus, antioxidant therapies have gained attention as adjuvants for castration-resistant PCa. Here, we repo...

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Detalhes bibliográficos
Publicado no:FASEB J
Main Authors: Lee, Joo Hyoung, Kang, Minsung, Wang, Hong, Naik, Gurudatta, Mobley, James A., Sonpavde, Guru, Garvey, W. Timothy, Darley-Usmar, Victor M., Ponnazhagan, Selvarangan
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2017
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5349799/
https://ncbi.nlm.nih.gov/pubmed/28069826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201601178R
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