Mitogen-induced distinct epialleles are phosphorylated at either H3S10 or H3S28, depending on H3K27 acetylation

Stimulation of the MAPK pathway results in mitogen- and stress-activated protein kinase 1/2 (MSK1/2)-catalyzed phosphorylation of histone H3 at serine 10 or 28 and expression of immediate-early (IE) genes. In 10T1/2 mouse fibroblasts, phosphorylation of H3S10 and H3S28 occurs on different H3 molecul...

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Detalhes bibliográficos
Publicado no:Mol Biol Cell
Main Authors: Khan, Dilshad H., Healy, Shannon, He, Shihua, Lichtensztejn, Daniel, Klewes, Ludger, Sharma, Kiran L., Lau, Veronica, Mai, Sabine, Delcuve, Geneviève P., Davie, James R.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2017
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5349788/
https://ncbi.nlm.nih.gov/pubmed/28077620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E16-08-0618
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