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Roles of histone deacetylases in epigenetic regulation: emerging paradigms from studies with inhibitors
The zinc-dependent mammalian histone deacetylase (HDAC) family comprises 11 enzymes, which have specific and critical functions in development and tissue homeostasis. Mounting evidence points to a link between misregulated HDAC activity and many oncologic and nononcologic diseases. Thus the developm...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
BioMed Central
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3320549/ https://ncbi.nlm.nih.gov/pubmed/22414492 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1868-7083-4-5 |
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