Roles of histone deacetylases in epigenetic regulation: emerging paradigms from studies with inhibitors

The zinc-dependent mammalian histone deacetylase (HDAC) family comprises 11 enzymes, which have specific and critical functions in development and tissue homeostasis. Mounting evidence points to a link between misregulated HDAC activity and many oncologic and nononcologic diseases. Thus the developm...

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Autores principales: Delcuve, Geneviève P, Khan, Dilshad H, Davie, James R
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2012
Materias:
Review
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3320549/
https://ncbi.nlm.nih.gov/pubmed/22414492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1868-7083-4-5
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