Stereoselective Actions of Methylenedioxypyrovalerone (MDPV) To Inhibit Dopamine and Norepinephrine Transporters and Facilitate Intracranial Self-Stimulation in Rats

The designer stimulant methylenedioxypyrovalerone (MDPV) is a potent reuptake inhibitor at transporters for dopamine (DAT) and norepinephrine (NET) that produces a constellation of abuse-related behavioral effects. MDPV possesses a chiral center, and the abused formulation of the drug is a racemic m...

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Udgivet i:ACS Chem Neurosci
Main Authors: Kolanos, R., Partilla, J. S., Baumann, M. H., Hutsell, B. A., Banks, M. L., Negus, S. S., Glennon, R. A.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5349769/
https://ncbi.nlm.nih.gov/pubmed/25688761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschemneuro.5b00006
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