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Allele-specific transcriptional activity of the variable number of tandem repeats of the inducible nitric oxide synthase gene is associated with idiopathic achalasia

BACKGROUND: Polymorphisms of genes involved in the regulation of the immune response are risk factors for achalasia, but their contribution to disease pathogenesis is unknown. Nitric oxide is involved both in immune function and inhibitory neurotransmission. OBJECTIVE: The objective of this article...

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Bibliografski detalji
Izdano u:United European Gastroenterol J
Glavni autori: Sarnelli, Giovanni, Grosso, Michela, Palumbo, Ilaria, Pesce, Marcella, D’Alessandro, Alessandra, Zaninotto, Giovanni, Annese, Vito, Petruzzelli, Raffaella, Izzo, Paola, Sepulveres, Rossana, Bruzzese, Dario, Esposito, Giuseppe, Cuomo, Rosario
Format: Artigo
Jezik:Inglês
Izdano: SAGE Publications 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5349359/
https://ncbi.nlm.nih.gov/pubmed/28344787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2050640616648870
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