Allele-specific transcriptional activity of the variable number of tandem repeats of the inducible nitric oxide synthase gene is associated with idiopathic achalasia

BACKGROUND: Polymorphisms of genes involved in the regulation of the immune response are risk factors for achalasia, but their contribution to disease pathogenesis is unknown. Nitric oxide is involved both in immune function and inhibitory neurotransmission. OBJECTIVE: The objective of this article...

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Publicat a:United European Gastroenterol J
Autors principals: Sarnelli, Giovanni, Grosso, Michela, Palumbo, Ilaria, Pesce, Marcella, D’Alessandro, Alessandra, Zaninotto, Giovanni, Annese, Vito, Petruzzelli, Raffaella, Izzo, Paola, Sepulveres, Rossana, Bruzzese, Dario, Esposito, Giuseppe, Cuomo, Rosario
Format: Artigo
Idioma:Inglês
Publicat: SAGE Publications 2016
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Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5349359/
https://ncbi.nlm.nih.gov/pubmed/28344787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2050640616648870
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