Selecting for Neurogenic Potential as an Alternative for Alzheimer’s Drug Discovery

BACKGROUND: Neurons die in Alzheimer’s disease (AD) and are not effectively replaced. An alternative approach to maintain nerve cell number is to identify compounds that stimulate the proliferation of endogenous neural stem cells in old individuals to replace lost neurons. However, unless a neurogen...

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Vydáno v:Alzheimers Dement
Hlavní autoři: Prior, Marguerite, Goldberg, Joshua, Chiruta, Chandramouli, Farrokhi, Catherine, Kopynets, Mariya, Roberts, Amanda J., Schubert, David
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5349322/
https://ncbi.nlm.nih.gov/pubmed/27149904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jalz.2016.03.016
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