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Selecting for Neurogenic Potential as an Alternative for Alzheimer’s Drug Discovery

BACKGROUND: Neurons die in Alzheimer’s disease (AD) and are not effectively replaced. An alternative approach to maintain nerve cell number is to identify compounds that stimulate the proliferation of endogenous neural stem cells in old individuals to replace lost neurons. However, unless a neurogen...

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Detalhes bibliográficos
Publicado no:Alzheimers Dement
Main Authors: Prior, Marguerite, Goldberg, Joshua, Chiruta, Chandramouli, Farrokhi, Catherine, Kopynets, Mariya, Roberts, Amanda J., Schubert, David
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5349322/
https://ncbi.nlm.nih.gov/pubmed/27149904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jalz.2016.03.016
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