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Sulfur transfer and activation by ubiquitin-like modifier system Uba4•Urm1 link protein urmylation and tRNA thiolation in yeast

Urm1 is a unique dual-function member of the ubiquitin protein family and conserved from yeast to man. It acts both as a protein modifier in ubiquitin-like urmylation and as a sulfur donor for tRNA thiolation, which in concert with the Elongator pathway forms 5-methoxy-carbonyl-methyl-2-thio (mcm(5)...

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Bibliographic Details
Published in:Microb Cell
Main Authors: Jüdes, André, Bruch, Alexander, Klassen, Roland, Helm, Mark, Schaffrath, Raffael
Format: Artigo
Language:Inglês
Published: Shared Science Publishers OG 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5349211/
https://ncbi.nlm.nih.gov/pubmed/28357324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15698/mic2016.11.539
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