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Endothelial Dll4 overexpression reduces vascular response and inhibits tumor growth and metastasization in vivo
BACKGROUND: The inhibition of Delta-like 4 (Dll4)/Notch signaling has been shown to result in excessive, nonfunctional vessel proliferation and significant tumor growth suppression. However, safety concerns emerged with the identification of side effects resulting from chronic Dll4/Notch blockade. A...
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| Publicado no: | BMC Cancer |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5348880/ https://ncbi.nlm.nih.gov/pubmed/28288569 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-017-3171-2 |
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