Adipose tissue fibrosis in human cancer cachexia: the role of TGFβ pathway

BACKGROUND: Cancer cachexia is a multifactorial syndrome that dramatically decreases survival. Loss of white adipose tissue (WAT) is one of the key characteristics of cachexia. WAT wasting is paralleled by microarchitectural remodeling in cachectic cancer patients. Fibrosis results from uncontrolled...

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Vydáno v:BMC Cancer
Hlavní autoři: Alves, Michele Joana, Figuerêdo, Raquel Galvão, Azevedo, Flavia Figueiredo, Cavallaro, Diego Alexandre, Neto, Nelson Inácio Pinto, Lima, Joanna Darck Carola, Matos-Neto, Emidio, Radloff, Katrin, Riccardi, Daniela Mendes, Camargo, Rodolfo Gonzalez, De Alcântara, Paulo Sérgio Martins, Otoch, José Pinhata, Junior, Miguel Luiz Batista, Seelaender, Marília
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2017
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5348844/
https://ncbi.nlm.nih.gov/pubmed/28288584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-017-3178-8
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