Adipose tissue fibrosis in human cancer cachexia: the role of TGFβ pathway

BACKGROUND: Cancer cachexia is a multifactorial syndrome that dramatically decreases survival. Loss of white adipose tissue (WAT) is one of the key characteristics of cachexia. WAT wasting is paralleled by microarchitectural remodeling in cachectic cancer patients. Fibrosis results from uncontrolled...

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Publicado en:BMC Cancer
Main Authors: Alves, Michele Joana, Figuerêdo, Raquel Galvão, Azevedo, Flavia Figueiredo, Cavallaro, Diego Alexandre, Neto, Nelson Inácio Pinto, Lima, Joanna Darck Carola, Matos-Neto, Emidio, Radloff, Katrin, Riccardi, Daniela Mendes, Camargo, Rodolfo Gonzalez, De Alcântara, Paulo Sérgio Martins, Otoch, José Pinhata, Junior, Miguel Luiz Batista, Seelaender, Marília
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2017
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5348844/
https://ncbi.nlm.nih.gov/pubmed/28288584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-017-3178-8
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