Prolyl oligopeptidase attenuates hepatic stellate cell activation through induction of Smad7 and PPAR-γ

Prolyl oligopeptidase (POP) is a serine endopeptidase widely distributed in vivo with high activity in the liver. However, its biological functions in the liver have remained largely elusive. A previous study by our group has shown that POP produced N-acetyl-seryl-aspartyl-lysyl-proline (AcSDKP) and...

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Publicat a:Exp Ther Med
Autors principals: Zhou, Da, Wang, Jing, He, Ling-Nan, Li, Bing-Hang, Ding, Yong-Nian, Chen, Yuan-Wen, Fan, Jian-Gao
Format: Artigo
Idioma:Inglês
Publicat: D.A. Spandidos 2017
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5348651/
https://ncbi.nlm.nih.gov/pubmed/28352366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2017.4033
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