Activation of phosphatidylinositol 3-kinase by insulin.

Insulin action appears to require the protein-tyrosine kinase domain of the beta subunit of the insulin receptor. Despite this, the identities and biochemical functions of the cellular targets of this tyrosine kinase are unknown. A phosphatidylinositol 3-kinase (PI 3-kinase) that phosphorylates the...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Ruderman, N B, Kapeller, R, White, M F, Cantley, L C
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1990
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC53485/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2154747/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.4.1411
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