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Activation of phosphatidylinositol 3-kinase by insulin.

Insulin action appears to require the protein-tyrosine kinase domain of the beta subunit of the insulin receptor. Despite this, the identities and biochemical functions of the cellular targets of this tyrosine kinase are unknown. A phosphatidylinositol 3-kinase (PI 3-kinase) that phosphorylates the...

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Bibliografiske detaljer
Main Authors: Ruderman, N B, Kapeller, R, White, M F, Cantley, L C
Format: Artigo
Sprog:Inglês
Udgivet: 1990
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC53485/
https://ncbi.nlm.nih.gov/pubmed/2154747
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