Genetic susceptibility of eight nonsynonymous polymorphisms in HLA-DRB1 gene to hepatocellular carcinoma in Han Chinese

BACKGROUNDS AND OBJECTIVE: Mounting evidence suggests that human leukocyte antigen (HLA) plays a central role in anti-virus and tumor defense. To test whether genetic variation in HLA-DRB1 gene, a key component of HLA system, can predict its predisposition to hepatocellular carcinoma (HCC), we there...

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Dettagli Bibliografici
Pubblicato in:Oncotarget
Autori principali: Shi, Yanhui, Zhai, Weiyu, Wang, Bin, Zhao, Dongmei, Jin, He, Wang, Yuefei, Zhang, Jidong, An, Hongjun, Fu, Zhongze, Zhao, Kun, Lu, Changzhu
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2016
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5348366/
https://ncbi.nlm.nih.gov/pubmed/27821814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13111
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