Sphk1 promotes breast epithelial cell proliferation via NF-κB-p65-mediated cyclin D1 expression

Lipid metabolism is crucially involved with the promotion of malignant progression and metastasis in various cancers. Growing evidence suggests that many types of cancers express high levels of sphingosine kinase 1 (Sphk1), which is known to mediate cell proliferation We hypothesized that Sphk1/sphi...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Oncotarget
Main Authors: Li, Shifei, Zhou, Yan, Zheng, Xiaodong, Wu, Xiujuan, Liang, Yueyang, Wang, Shushu, Zhang, Yi
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2016
Teme:
Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5348342/
https://ncbi.nlm.nih.gov/pubmed/27811358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13013
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