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Sphk1 promotes breast epithelial cell proliferation via NF-κB-p65-mediated cyclin D1 expression

Lipid metabolism is crucially involved with the promotion of malignant progression and metastasis in various cancers. Growing evidence suggests that many types of cancers express high levels of sphingosine kinase 1 (Sphk1), which is known to mediate cell proliferation We hypothesized that Sphk1/sphi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Oncotarget
Hauptverfasser: Li, Shifei, Zhou, Yan, Zheng, Xiaodong, Wu, Xiujuan, Liang, Yueyang, Wang, Shushu, Zhang, Yi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5348342/
https://ncbi.nlm.nih.gov/pubmed/27811358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13013
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