Targeting the receptor tyrosine kinase RET in combination with aromatase inhibitors in ER positive breast cancer xenografts

The majority of breast cancers are estrogen receptor positive (ER+). Blockade of estrogen biosynthesis by aromatase inhibitors (AIs) is the first-line endocrine therapy for post-menopausal women with ER+ breast cancers. However, AI resistance remains a major challenge. We have demonstrated previousl...

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Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Andreucci, Elena, Francica, Paola, Fearns, Antony, Martin, Lesley-Ann, Chiarugi, Paola, Isacke, Clare M., Morandi, Andrea
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2016
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5348339/
https://ncbi.nlm.nih.gov/pubmed/27602955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11826
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