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Safety of High-Dose Acyclovir in Infants with Suspected and Confirmed Neonatal Herpes Simplex Virus Infections

BACKGROUND: Acyclovir is used to treat herpes simplex virus (HSV) disease in infants. Treatment with high dose acyclovir, 60 mg/kg/day, is recommended; however, the safety of this dosage has not been assessed in the past 15 years, and this dosage is not currently approved for infants by the US Food...

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Vydáno v:Pediatr Infect Dis J
Hlavní autoři: Ericson, Jessica E., Gostelow, Martyn, Autmizguine, Julie, Hornik, Christoph P., Clark, Reese H., Benjamin, Daniel K., Smith, P. Brian
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5348260/
https://ncbi.nlm.nih.gov/pubmed/27977557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/INF.0000000000001451
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