The P2Y(2) nucleotide receptor is an inhibitor of vascular calcification

BACKGROUND AND AIMS: Mutations in the 5′-nucleotidase ecto (NT5E) gene that encodes CD73, a nucleotidase that converts AMP to adenosine, are linked to arterial calcification. However, the role of purinergic receptor signaling in the pathology of intimal calcification is not well understood. In this...

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Veröffentlicht in:Atherosclerosis
Hauptverfasser: Qian, Shaomin, Regan, Jenna N., Shelton, Maxwell T., Hoggatt, April, Mohammad, Khalid S., Herring, Paul B., Seye, Cheikh I.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5348113/
https://ncbi.nlm.nih.gov/pubmed/28038380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.atherosclerosis.2016.12.014
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